We offer various molecular biological, microbiological and biotechnological testing and development services. This can be studies or the implementation of a project. We accompany you from the idea of a new product or a new process to its market launch.
Our accredited testing laboratory (department for food testing) at the fzmb also offers a wide range of services in the field of microbiological and chemical analyses.
The veterinary clinic at our institute treats large and small animals in almost all medical areas. In addition to the small animal practice, our veterinary clinic focuses in particular on the medical care of horses.
Diagnostic systems
Development and production of microarrays
Microarrays consist of a large number of microscopically small spots that can be precisely applied to a solid surface using high-precision dispensers. For example, more than 700 spots can be applied in a single well of a 96-well microtiter plate. Customized development In the INTER-ARRAY division at fzmb, we accompany you through all development phases of microarrays, from the feasibility study to pilot production. Following successful development, our ISO-certified production capacities are available to you as a contract manufacturing partner. Quality control of microarrays The focus is on the high quality of microarray products. For production, the dispensing systems operate in a climate-controlled environment with inline QC software, so that quality control of all arrays produced is guaranteed.
Information Further information can be found on our website www.inter-array.com. Contact Katrin Frankenfeld Head of Biotechnology Department Phone +49 3603 – 833 141 Email
Development and production of multiparameter tests
Protein and antibody microarray technology offers enormous potential for a wide range of diagnostic applications. Miniaturized, parallelized immunoassays as well as DNA-based microarrays are ideal for generating maximum diagnostically relevant information with small sample and reagent volumes. A microarray thus saves a lot of time, valuable samples and expensive raw material. Application in human and veterinary medicine The use of microarrays in human and veterinary diagnostics is interesting for all applications in which several analytes can be determined from a single sample. Typical examples of multiparameter analysis are allergy and food intolerance tests, the diagnosis of autoimmune, metabolic and infectious diseases, and cancer diagnostics. The technology offers excellent prospects for new approaches to individualized diagnostics and personalized medicine. Multi-parameter analysis in various formats In the business unit INTER-ARRAY at the fzmb we carry out new developments of various multiparameter tests. Standard detection formats such as ELISA, lateral flow strips, and microfluidic assays can be used, as well as custom platforms. Our team offers flexible support for feasibility, validation as well as production projects for various microarray based assays. In addition to completely new developments, it is also possible to transfer existing tests to the microarray platform. Information Further information can be found on our website www.inter-array.com. Contact Katrin Frankenfeld Head of Biotechnology Department Phone +49 3603 – 833 141 Email
High precision dispensing
In order to be able to apply very small volumes of capture molecules (from picoliters to microliters) with high precision to any surface, a great deal of experience is required in addition to very good dispensing systems. Our INTER-ARRAY division at fzmb is equipped with a large number of state-of-the-art microdispensers and has many years of specialist know-how.
From design to data analysis: Exclusive printing offers
With our established technologies for high-precision dispensing and our many years of experience from design to data analysis, we create an exclusive printing offering in the life science sector. We offer this all-round service at an attractive price/performance ratio. The focus here is on high quality and short production times. Spotting a wide variety of substances The substances that can be spotted include antibodies, other proteins and peptides, oligonucleotides, carbohydrates, cells and cell lysates, particles and chemical compounds as well as special molecules provided by the customer. The substrates to be coated are glass and polymer slides, microtiter plates and microcavities, membranes and microfluidic chips, wafers, biosensors and individualized surfaces. Information Further information can be found on our website www.inter-array.com. Contact Katrin Frankenfeld Head of Biotechnology Department Phone +49 3603 – 833 141 Email
Immunoassay development
The lateral flow assay (LFA) is an immunological strip test. It combines the principle of thin-layer chromatography with antibody-based detection (colorimetric, enzymatic or fluorescence). An LFA is the basis for cost-effective, highly sensitive and reliable detection of a wide range of analytes. As a point-of-care test (POCT), lateral flow assays find multiple applications e.g. in immunodiagnostics or in the analysis of environmental and food samples. The ELISA (Enzyme-linked Immunosorbent Assay) is used for the qualitative and/or quantitative detection of an analyte (antigen) in a sample. In addition, many samples can be analyzed in parallel and automated in a laboratory environment. We develop LFAs and ELISAs from feasibility to small-scale production or preparation for large-scale production. These immunoassays can be used to diagnostically detect a wide variety of analytes in complex sample matrices. Highly specific and affine monoclonal and polyclonal antibodies are required for reliable selective binding of the analyte in a liquid phase or tissue sample. Their production and application-related characterization is one of our core competencies. Reliable detection of biological structures with high sensitivity Imunoassays can detect the desired analytes down to the nanogram range, in some cases even in the picogram range. Qualitative and quantitative detection is possible from a wide variety of biological samples with complex compositions without pretreatment. The fzmb develops fast, highly specific test systems with colorimetric, fluorescence or chemiluminescence-based readout for any parameter.
Performance overview
- Development of ELISAs for the qualitative detection of micro- and macromolecules (formats: indirect ELISA, sandwich ELISA).
- Development of ELISAs for qualitative detection of analytes (format: sandwich ELISA).
- Development of lateral flow assays (LFA) for qualitative/quantitative detection of biomarkers.
- Optimization of assay components and steps for the benefit of sensitivity and assay speed
- Validation of the developed ELISA/ LFA
Highly sensitive 4in1/ 6in1 antigen rapid tests
The lateral flow assay (LFA) is an immunological strip test. It combines the principle of thin-layer chromatography with antibody-based detection. At the fzmb, we develop LFAs from feasibility to small series or preparation for large-scale production. More information from a rapid test Is it Covid-19, RSV or influenza (A or B)? If more than one question arises the answer should be sufficient, too We have therefore developed a new platform for lateral flow assays. On this new platform, up to 6 different tests can be integrated in one run (6in1 combination tests). Use of special nanoparticles Special fluorescent nanoparticles are used as the basis, which we conjugate with the corresponding antibodies. Thus, we achieve not only multiplexing (several tests combined). The sensitivity (detection limit of the respective analyte) is improved by up to 10 times.
The combination tests are read out digitally using a corresponding read-out device. Two variants are available for this purpose: For laboratory applications, commercially available devices (lateral flow fluorescence readers) can be used. In cooperation, we also offer solutions ready for series production for home use.
PDF Highly sensitive combination rapid tests
Specific antibodies
Production of monoclonal antibodies
Monoclonal antibodies can be generated for almost any antigen or epitope. These can be used to establish diagnostic test systems of various formats for the detection of these structures, as they bind the desired target structure in a highly specific manner. Rapid development and characterization for specific applications We develop specific monoclonal antibodies in the mouse host organism. In addition to antibody production, we can also supply the equivalent antigen (recombinant and native proteins, peptides, microorganisms and their structures). For rapid downstream development, we offer antibody characterization and matched pair analysis. For this purpose, we use the classic hybridoma technique. The antibodies can therefore be used, for example, in high-quality and effective test systems for the specific diagnosis of the desired antigens.
Performance overview
- Production/procurement of the antigen (immunization, screening)
- Immunization of laboratory animals
- Titration of the sera (verification of the immune response)
- Fusion of mouse spleen cells with mouse myeloma cells (hybridoma technique).
- Screening for antibody-secreting clones, specificity testing
- Characterization of antibodies (isotyping, expression performance, affinity to the antigen of interest).
- Establishment of a permanent cell line for the selected clones, incl. Cryopreservation and storage in liquid nitrogen
- Antibody production (cell culture supernatant) and isolation of antibodies (affinity chromatography)
- Integration in immunoassays of different formats (ELISA, LFA, IFAT)
Overview of antibody-producing cell lines at the fzmb
Antibodies directed against
- American foulbrood
- Aminocellulose
- Anti-Trypsin (Alpha1Pi)
- Archaea (e.g. Methanosarcinae)
- BBI
- Clostridium botulinum toxin C
- Clostridium botulinum toxin A
- Burkholderia mallei
- Brucella abortus
- Complement component C3A
- Coxiella burnetii
- Deoxynivalenol
- DY dyes and quenchers
- Factor X
- Factor Xa
- Heparin Binding Protein
- HIS Day
- Human Immunoglobulin A
- Human Immunoglobulin G
- Lactobacillus brevis
- Lactoferrin
- Legionella pneumophila
- Lipid A (Salmonella)
- Listeria monocytogenes
- LukF
- Lunasin
- MAP, Mycobacterium avium paratuberculosis (inactivated cells).
- eMMP9 (equine matrix metallo proteinase 9)
- NDV, Newcastle Disease Virus
- fNTproBNP (feline natriuretic brain peptide)
- cNTproBNP (canine Natriuretic Brain Peptide)
- Parvovirus
- PBP2a
- Pediococcus damnosus
- Pediococcus inopinatus
- Procalcitonin
- Rotavirus
- SAG1 (Toxoplasma gondii)
- Salmonella
- SARS-CoV-2 (human Severe Acute Respiratory Syndrome Coronavirus 2)
- SP-10 (human sperm protein, ACRV-1)
- Transferrin
- Troponin
- Felines trypsinogen
- Zearalenone
Production of recombinant antibodies (horse)
In human medicine, so-called chimeric (about 75 % human) and humanized antibodies have been used for more than 20 years. There are now a large number of approved therapeutic antibodies for human use. As a company with close ties to veterinary medicine, we have set ourselves the task of developing innovative immunological therapies for pets.
Specific antibodies for therapy We are developing recombinant horse-specific antibodies for subsequent therapeutic use in horses. The current focus is the development of an antibody against matrix metalloproteinase 9 (MMP-9). This antibody is intended to serve as a specific therapeutic agent, for example, for the targeted treatment of arthritis, wound healing disorders and equine sarcoid. But also in other diseases in which an overexpression of matrix metalloproteinase 9 (MMP-9) is causally involved, a new therapeutic option is to be created. In this way, pathological processes that arise due to the tissue-degrading properties of MMP-9 can be specifically stopped at the site of development. recombinant equine immunoglobulins Molecular genetic methods have been developed for the production of equine recombinant antibodies in cell culture. Furthermore, these techniques can be used to produce other equine immunoglobulins, for example, as passive immunotherapeutics against equine infectious diseases. Based on the choice of subtype specificity and the regulatory Fc region, beyond the desired antigen specificity, the potential as a modulator can be used to strengthen the body’s immune system, e.g. against an existing cancer. Go with us conversation about your concern and issue. Our ambition is to work with you to lay the foundations for innovative and specific immunotherapy for the horse. If we have aroused your interest, please do not hesitate to contact us. Contact Dr. Ina-Gabriele Richter Phone +49 3603 – 833 177 Email
Production of polyclonal antibodies
We produce artificial human immune sera by means of in-vitro immunization.
Contact Dr. Ina-Gabriele Richter Phone +49 3603 – 833 177 Email
Matched Pair Antibodies
Whether a selected matched-pair antibody pair works well in a planned application depends on many factors and cannot be predicted. We therefore not only offer the development of specific monoclonal antibodies (including the identification of matched pairs) for e.g. Immunoassay developments on. For best performance of a Matched Antibody Pair, we test the performance of these antibody pairs in the desired application. This early testing of the antibodies in the target application (ELISA, LFA with immunogold or fluorescent nanoparticles, IFAT) enables targeted antibody selection or development and thus allows the best possible performance. Performance overview
- Development of monoclonal antibodies against desired target structures
- Antibody characterization (isotyping, expression)
- Matched pair analysis in target format (sandwich ELISA, lateral flow assay LFA):
- Coupling to structures for colorimetric or fluorimetric detection (biotin, HRP, AP, fluorescent dyes).
- Immobilization of the catcher candidates
- Detectors analysis
- Testing of possible combinations
- Buffer optimization
Analysis of food, drinking water and cosmetics
Laboratory for food testing
The testing laboratory in the food testing department at the fzmb has been an independent service provider for food safety and consumer protection since 1994. The laboratory is accredited by the German Accreditation Body (DAkkS) in accordance with DIN EN ISO 17025.
Which products do we analyze?
- Meat and meat products
- Milk and dairy products
- Ice cream
- Bakery products
- Cereals and cereal products
- Delicatessen salads
- Fish
- ready-to-eat meals
- Drinking water
- other products on request
What services do we offer?
Food Microbiology
- Testing in accordance with legal requirements under Regulation (EC) No. 2073/2005 or in accordance with requirements of the German Society for Hygiene and Microbiology (DGHM) for products at retail level
- Surface germ content on carcasses
- Pathogen monitoring by means of PCR
- Salmonella antibodies in meat juice and serum
Industrial hygiene
- Control of cleaning / disinfection
- Control of personnel hygiene
- Airborne germ content (incl. sampling)
- Pathogen monitoring
Food Chemistry
- Mycotoxins (ochratoxin A)
- Main ingredients
- Nutritional values
- Nitrite/ Nitrate
chemical-physical
- aw value
- pH value
- Protective gas measurement
Drinking water
- Sampling
- Microbiology according to drinking water ordinance
other services
- Sample collection in modern refrigerated vehicle
- Checking the declaration for legal conformity
- Sensory testing
- Hygiene training
- Plant inspections/ hygiene audits
- Cross-check expert opinion
- Consulting and assistance with food law issues and the solution
specific problems in the following areas:
- Development, production, storage, labeling and marketing of food products.
PDF List of test methods Food testing department Contact Steffi Leuschke State-certified food chemist Phone +49 3603 – 833 173 Email
Microbiological and chemical analysis of food
We carry out microbiological, chemical and chemical-physical testing of foodstuffs, including product-specific testing:
- Pathogen
- Spoilage agent
- Compliance with legal requirements (e.g. VO 2073/2005, Zusatzstoff-Zulassungsverordnung, Käseverordnung)
- Compliance with microbiological guideline and warning values of the German Society for Hygiene and Microbiology (DGHM)
- aw value and pH value
- Determination of food ingredients
- Compliance with specifications of the guiding principles of the German Food Book
- Nutritional value determination “BIG 7
- Determination of ochratoxin A in cereals and cereal products by HPLC.
- Detection of antibodies against Salmonella serovars of groups B, C, D and E in meat juice and blood products by ELISA, entry of results in the Qualiproof database.
- Checking of markings for legal conformity
Contact Steffi Leuschke State-certified food chemist Phone +49 3603 – 833 173 Email
Microbiological testing of cosmetics
Microbiological product safety is one of the most important factors in the safety assessment of cosmetic products. Our analytical laboratory tests the microbiological quality of cosmetic products as well as the raw materials used. As part of operational hygiene monitoring, we offer manufacturers of cosmetics various tests of process water or production water, room air and surfaces as well as packaging materials. The spectrum of our laboratory includes the following analysis methods:
- Preservation load test
(Assessment of the preservation of cosmetic formulations)
- Testing for microbial contamination
- Detection of specific microorganisms
- Checking the cleaning and disinfection of surfaces and consumer goods
- Checking the indoor air quality
PDF Test laboratory for cosmetics
Contact Steffi Leuschke State-certified food chemist Phone +49 3603 – 833 173 Email
Examination of air, objects, environmental samples
- Checking the cleaning and disinfection of surfaces and consumer goods
- Checking the indoor air quality
- Verification of personnel hygiene
Contact Steffi Leuschke State-certified food chemist Phone +49 3603 – 833 173 Email
Drinking water testing
Drinking water is a foodstuff and is therefore subject to strict regulations. The testing of drinking water in our laboratory is carried out in accordance with the Ordinance on the Quality of Water for Human Consumption (Drinking Water Ordinance – TrinkwV 2001). As an accredited laboratory (approved testing center according to § 40 para. 1 of the Drinking Water Ordinance), we are happy to check whether the quality of your drinking water complies with Directive 98/83 EC.
- Checking the microbiological drinking water quality (colony count at 22°C and 36°C, coliform germs, Escherichia coli, enterococci)
We also offer:
- Determination of Pseudomonas aeruginosa
- Determination of Clostridium perfringens
- Testing drinking water installations for Legionella spp.
Note: If the analysis of your drinking water has to meet official requirements, a sample must be taken by our accredited personnel.
PDF Test laboratory drinking water
Contact Steffi Leuschke State-certified food chemist Phone +49 3603 – 833 173 Email
Biological recyclables
Inactivation of bacteria and viruses
The use of inactivated microorganisms as control material or for immunization for antibody production can minimize the risk of infection and contamination. For this purpose, the corresponding microorganisms are inactivated by a special UV treatment.
UV inactivation of microorganisms
UV-inactivated bacteria and viruses are particularly well suited as microbiological control material for scientific or medical purposes. The high-energy UV light damages the DNA, causing it to be inactivated. However, the macromolecular outer surface remains intact. UV-inactivated bacteria are therefore extremely useful for the production of antibodies against surface antigens.
If inactivated bacteria are used as reference material to vital bacteria, comparable results are obtained. UV-inactivated microorganisms are also ideal for evaluating molecular tests as standardized, independent quality controls.
Inactivation according to your specifications
We offer UV-inactivated microorganisms as whole cell preparations (e.g. inactivated bacteria such as Legionella or Streptococcus or other species according to BSL1 and BSL2). You receive the UV-inactivated MOs in suspension with a set cell count and determine the desired buffers and additives.
Please feel free to contact us so that we can discuss your individual requirements.
Literature
Mertens-Scholz, K., Moawad, A. A., Liebler-Tenorio, E. M., Helming, A., Andrack, J., Miethe, P., Neubauer, H., Pletz, M. W., Richter, I. G., (2024). Ultraviolet C inactivation of Coxiella burnetii for production of a structurally preserved whole cell vaccine antigen. BMC Microbiol 24(1): 118.
Information as PDF
Contact
Dr. Ina-Gabriele Richter Tel. +49 3603 – 833 177 Email
Inactivation of bacteria and viruses
The use of inactivated microorganisms as control material or for immunization for antibody production can minimize the risk of infection and contamination. For this purpose, the corresponding microorganisms are inactivated by thermal, chemical or UV treatment. Customer-specific inactivation of microorganisms We offer inactivated microorganisms as whole cell preparations (e.g. inactivated bacteria such as legionella or streptococci) as standardized, independent quality controls for the evaluation of molecular tests. We can also carry out customized inactivation, e.g. of bacteria, according to your specifications. You determine the desired concentrations, buffers and additives. Please feel free to contact us so that we can discuss your individual requirements.
Thermal inactivation of bacteria and viruses
Information as PDF
Contact Dr. Ina-Gabriele Richter Phone +49 3603 – 833 177 Email
BioCellulose (Made in Germany)
Ultra thin & ultra light
Natural skin feeling
Our BioCellulose is a pure natural material. It is significantly purer than plant cellulose and consists of a stable mesh of ultra-thin fibers that adapt perfectly to any skin contour. The masks are particularly light and transparent and are therefore even interesting for those who have not used fleece masks before.
BioCellulose as active ingredient carrier
In its meshwork of millions of fine fibers, our BioCellulose stores cosmetic active ingredient solutions for the treatment and care of the skin. By optimally adapting to the skin surface, the active ingredient molecules are delivered to the skin in a targeted manner and very good cosmetic results are achieved.
Application
Easy to use in the beauty salon or at home The BioCellulose masks are incredibly light and thin. As a result, they lie almost invisibly on the face. The application of the masks is very simple. The carrier material used allows easy application of the BioCellulose to the skin. The two mask parts allow adjustment to any face size. Due to the extremely good adhesion of the BioCellulose to the surface of the face, the client has a high degree of freedom of movement during the treatment.
Ideal combination with apparative treatment methods The BioCellulose masks provide a unique basis for combining with apparative treatment methods. The material of the masks not only allows optimum release of the active ingredients but also perfect transfer of the physical effects in order to positively influence the skin’s regeneration processes and stimulate metabolic processes.
Production
Development, production and packagingWe act as a contract manufacturer for the production of cosmetic masks to customer specifications. Our BioCellulose is biotechnologically extracted from glucose in Germany and processed into masks. We impregnate the masks with our customers’ active ingredients or provide a product formulation. We are happy to advise you on the choice of active ingredients.
Research and development
We implement the ideas that our customers bring to us. The production of samples is part of our service offer. Thanks to our own perfectly equipped laboratories, our competent chemists, biologists and laboratory technicians are able to offer comprehensive research and development services.
Quality
We have been producing BioCellulose at the highest level for 20 years. Our experienced team works to produce high quality products to exacting standards. The GMP-compliant production is certified according to DIN ISO 9001. The product is dermatologically tested and is manufactured entirely in Germany. We guarantee fast order processing. Contact Dr. Ina-Gabriele Richter Phone +49 3603 – 833 177 Email
Data Science & Optical Analytics
Hyperspectral Imaging (HSI)
Quality control of production flows An important field of application for hyperspectral imaging is quality control, e.g. in food production. Fast and continuous data acquisition and evaluation in real time creates an excellent basis for inline controls of production flows. Hyperspectral imaging (HSI) Every surface and every material has its own spectral signature. This characteristic signature can be recorded with a hyperspectral camera. Algorithms evaluate the signatures and assign them to qualitative and quantitative properties of the objects being measured. How HSI works As with a scanner, many hyperspectral cameras record their images line by line. For this purpose, the sample to be examined is moved under the camera. A characteristic spectrum of the measurement object within a defined wavelength range is detected in each captured pixel. Data evaluation in real time Modern evaluation methods make it possible to generate very detailed information about the measurement object from the highly complex measurement data in real time. For example, the quantitative chemical composition of food can be determined. The method also enables the detection of foreign objects as well as the detection of quality deviations or contamination of individual objects in the production flow. Continuous data acquisition and evaluation enables complete coverage of the entire product flow. The often time-consuming and unrepresentative taking of random samples is no longer necessary. HSI integration in your company With our HSI modules, objects from a few micrometers up to 60 cm can be analyzed in the wavelength range of 400 – 2500 nm. Our laboratory first performs preliminary examinations of your measurement objects and material samples. Based on the results, we configure a customized in-process system for you, incorporating special AI-based evaluation methods.
PDF Hyperspectral Imaging
Contact Florian Meuche Head of Device Development Phone +49 3603 – 833 194 Email
NIR spectroscopy
Organic samples absorb light in the near-infrared (NIR) wavelength range of 800-2500nm. Substances contained in the sample, such as proteins, fats, sugar and water components, generate a characteristic NIR spectrum. The analysis can be performed both qualitatively and quantitatively. Physical parameters such as particle size or pH also influence the shape of the NIR spectrum and can be determined. NIR spectroscopy thus offers fast, non-contact and precise measurement results, e.g. in the food and feed industry. Compared to chemical analyses, NIR measurements are much faster (>60 sec), require no special sample preparation and can analyze a large number of parameters in parallel. How NIR spectroscopy works The special excitation of the sample excites characteristic molecular vibrations. The vibrational states within the sample are reflected in the detected NIR spectrum. An analysis of the shape and position of the measured spectrum makes it possible to calculate the chemical composition/physical parameters of the sample. Integration of NIR spectroscopy into your company First, your samples are measured in our spectroscopy laboratory. At the same time, your desired target parameters are determined in our accredited analysis laboratory. Then the NIR spectrometer system mylab-NIR Analyzer and evaluation model is optimized for your measurement task. Integration into your production process is individually tailored to your requirements. Contact Florian Meuche Head of Device Development Phone +49 3603 – 833 194 Email
Ion Mobility Spectrometry (IMS)
Rapid analysis of volatile substances Ion mobility spectrometry (IMS) analyzes volatile compounds for their chemical composition. It is characterized by low detection limits (lower ppb range) and short measurement times (approx. 20 sec). How IMS works By heating the sample in a defined manner, the chemical substances are converted into the gas phase. The now gaseous substances are first ionized in the IMS. Driven by an electric field, the ions move through a gas-filled tube (drift tube). In the drift tube, the ions encounter gas molecules (e.g. air). The larger the ions in a sample, the more frequently they collide with the gas molecules and the longer they take to pass through the drift tube. After passing through the drift tube, a detector determines the drift time. The longer the drift time, the greater the molecular weight of an ion.
Examination of complex gas samples
For the analysis of complex gaseous samples, sample pre-separation by gas chromatography (GC) is a suitable method. The instrument configuration established at fzmb allows the analysis of light to medium volatile compounds up to a boiling point of 120 C°.
The range of substances that can be analyzed includes organic compounds such as hydrocarbons, aldehydes, ketones, alcohols, esters and amines.
Data evaluation
Range of services
- Fingerprint analytics
Comparative analysis of two different samples
(e.g. healthy vs. sick, treated vs. untreated).
Substratification for the identification of differentially expressed substances
- Identification of unknown substances (e.g. by GC-MS)
- Quantitative analysis of known (or previously characterized) substances
IMS integration in your company Areas of application at the fzmb:
- Microbiology and diagnostics of infections
- Reproductive medicine in farm animals
- Proof of medication for sport horses and food-producing animals
- Detection of ingredients in animal tissues
- Detection of impurities and additives in plastics
PDF Ion Mobility Spectrometry
Contact Florian Meuche Head of Device Development Phone +49 (0)3603 – 833 194 Email
Development of optical measuring instruments: Feasibility studies and validations
Optical measuring devices The composition and surface properties of materials can be characterized by interactions between light and matter. Modern optical analysis devices use physical effects such as absorption, reflection, transmission or the scattering of light to measure certain properties of a sample. Clever development saves costs Precise knowledge of the optical properties of the samples to be examined is essential for the development of efficient and cost-optimized optical analysis devices. Based on this knowledge, optimally tailored technical solutions can be designed. This reduces both development time and costs (e.g. for hardware). State-of-the-art test laboratory and expertise With our extensively equipped spectroscopy laboratory, our expertise in the field of optical measurement technology, modern simulation tools and innovative AI-based evaluation methods, we support you in the development of optimized optical measurement and analysis devices. Our services
- Measurement of absorption, reflection, transmission and scattering in the wavelength range of 200 – 4000 nm (UV – MIR) for the identification of problem-relevant wavelengths
- Simulation of the position and performance of light sources for the selection of suitable components
- Simulations for the optimization of beam paths
- Simulation of required detector areas for photodiodes
- Consulting on the design of electronic circuits for signal acquisition and processing
Contact Florian Meuche Head of Device Development Phone +49 3603 – 833 194 Email
Overview services
- Measurement of absorption, reflection and transmission in the wavelength range from 200 – 2,800 nm
- Scattered light measurements
- time-resolved fluorescence spectroscopy
- Near Infrared Spectroscopy
- Hyperspectral measurements in the wavelength range from 400 – 2,500 nm
- Development of chemometric models for NIR spectroscopy
- Development of AI-based evaluation methods for hyperspectral measurement data.
- Radiation optical simulations
- CAD modeling and 3D printing
Overview device equipment
- Stratasys OBJET 30 Prime Desktop 3D Printer
- Ocean Optics HR4000 CG UV-NIR Spectrometer
- BRUKER MPA – FT- NIR Spectrometer
- Hamamatsu FT – IR Spectrometer C12606-02
- ARCoptix FT- MIR Rocket 6.0
- Horiba Fluolog FL3-22
- Headwall Photonics VNIR Hyperspectral Imaging System
- SpecIm SP SP-sCMOS-CL50-v10E VIS-NIR Hyperspectral Imaging System
- SpecIm SP-SWIR-CL-400-N25E SWIR Hyperspectral Imaging System
Services of the veterinary clinic
The medical services of the equine clinic can be found on the website of the Bad Langensalza Veterinary Clinic.
The services of the small animal practice can be found on the website of the veterinary clinic Bad Langensalza here.