Inactivated bacteria

Standardized independent quality controls for evaluation of molecular tests
Using inactivated bacteria for immunization and as reference material in the production of antibodies can minimize the risk of contamination and infection. The most common means of inactivation are thermal or chemical treatment of cultured bacteria. Both procedures can alter the morphology and antigenicity of bacteria, rendering them unsuitable for many applications.

During UV inactivation, bacterial DNA is damaged by energetic light. This renders the bacteria noninfectious but leaves their macromolecular surface largely intact. UV inactivated bacteria are therefore uniquely useful for the production of antibodies against surface antigens. When used as reference material their physical properties closely match those of live bacteria, leading to readily comparable test results.

more Information

We supply you with UV-inactivated bacteria. You determine the desired concentrations, buff-ers and additives. We can also supply freeze-dried UV-inactivated bacteria, so this is kept as a powder and can be resuspended before use.

contact

Katrin Müller-Zahm
Department Cellbiology

fzmb GmbH, Research Centre of Medical Technology and Biotechnology
Geranienweg 7
D-99947 Bad Langensalza / Germany
Phone: +49 (0)3603 833 177
Fax: +49 (0)3603 833 150
Anfrage per E-Mail: kzahm(at)fzmb.de


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